Experience

Experience grounded in real-world decisions

Our founders have contributed to research and applied projects across evidence synthesis, indirect comparisons, survival modelling and HTA. Explore selected examples of our work and scientific contributions.

Publication highlights

87Network meta-analysis & meta-regression
35Population-adjusted indirect comparisons
23Advanced survival & endpoint modelling
15Economic modelling for HTA

Recent conference presentations

YearPresentationMeeting
2026Which route? Choosing a method for non‑proportional hazards that works for Joint Clinical Assessment and economic modelsISPOR Europe
2025What Is Your Estimand? Navigating Conditional and Marginal Effects in Cost-Effectiveness ModelingISPOR Europe
2025Clinical Trial Design, Beyond the RegulatoryISPOR
2025Large-Language Models to Complement and Augment Literature ReviewISPOR
2024Role of Global ITC Programs in Supporting Europe's Joint Clinical Assessments: Insights From Global and EU ExpertsISPOR Europe
2024Advanced Methods for Matching-Adjusted Indirect ComparisonISPOR
2024Adjusting Survival Estimates for Treatment Switching: New Guidance and the Role of Real-World EvidenceISPOR Europe
2024Structural Uncertainty in Evidence Synthesis: Model Averaging in Bayesian ML-NMRISPOR Europe
2023Apples and Oranges in Anchored Indirect Treatment Comparisons – Is There More to It Than Effect Modifiers?ISPOR
2023Alternative Network Meta-Analysis Methods in the Presence of Non-Proportional HazardsISPOR
2023Indirect Treatment Comparisons of Time-to-Event Outcomes with Mismatched “Time Zero”ISPOR podium

Ready to solve your evidence challenge?

Tell us about your evidence question. Based in Canada, working globally.

founders@unpuzzleheor.ca